Vysov-M 50/500 Mg Tablet (Vildagliptin/Metformin)

Description

Introduction

Vysov-M 50/500 mg Tablet contains vildagliptin 50 mg and metformin hydrochloride 500 mg. It is used to help control blood glucose in adults with type 2 diabetes. It is taken as part of a treatment plan that includes appropriate food choices and physical activity. A prescriber determines whether this combination and strength are suitable for the person taking it.

What Is It?

Vysov-M is an oral tablet containing two medicines. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin is a biguanide. Each tablet contains a fixed amount of both ingredients, so one ingredient cannot be adjusted without changing the other.

This combination may be prescribed when metformin alone does not adequately control blood glucose, or when both ingredients are already being taken as separate tablets. Vysov-M is not used to treat type 1 diabetes or diabetic ketoacidosis.

How Does It Work?

Vildagliptin slows the breakdown of incretin hormones. This helps the pancreas release insulin when blood glucose is high and reduces the release of glucagon, a hormone that raises blood glucose. Metformin mainly reduces glucose production by the liver and improves the body’s response to insulin. Together, these actions help lower blood glucose in type 2 diabetes.

Common Uses

• Helping control blood glucose when metformin alone has not provided adequate control.
• Providing vildagliptin and metformin in one tablet when both have been prescribed and this strength is appropriate.
• Use with other diabetes medicines when a prescriber determines that additional treatment is needed. Other medicines may change the risk of low blood glucose.

Available Strengths

This family is available in 500 mg, 1000 mg.

Key Features

• Contains vildagliptin 50 mg and metformin hydrochloride 500 mg per tablet.
• Combines two medicines with different actions in one oral tablet.
• Has a fixed ingredient ratio; the amount of either ingredient cannot be changed independently.
• Is intended for adults with type 2 diabetes as part of an overall treatment plan.

Benefits

• Can improve blood glucose control when metformin alone is insufficient and adding vildagliptin is appropriate.
• Provides both prescribed ingredients in one tablet at the 50/500 mg strength.
• May reduce the number of separate tablets needed when a person is already taking both ingredients at suitable doses.

Possible Side Effects

• Nausea, vomiting, diarrhoea, abdominal pain and loss of appetite can occur, particularly because of metformin.
• Headache, dizziness, weakness or a change in taste may also occur.
• Low blood glucose is more likely when Vysov-M is taken with insulin or a sulfonylurea.
• Lactic acidosis, pancreatitis, liver problems and severe allergic reactions are serious risks that need prompt medical assessment.
• Seek urgent medical help for severe or persistent abdominal pain, repeated vomiting, unusual breathing, marked weakness, yellowing of the skin or eyes, or swelling of the face or throat.

Precautions

• Kidney function should be checked before and during treatment. Reduced kidney function can allow metformin to accumulate and increase the risk of lactic acidosis.
• Tell the prescriber about liver disease, heart problems, heavy alcohol use, serious infection, dehydration or a history of pancreatitis.
• Do not take Vysov-M if you are allergic to vildagliptin, metformin or another ingredient in the tablet.
• Ask a healthcare professional to review diabetes treatment if you are pregnant, planning pregnancy or breastfeeding.

Additional Precautions

• Blood glucose, kidney function and liver function may need monitoring during treatment.
• Long-term metformin use can lower vitamin B12 levels. Seek assessment for unexplained anaemia, numbness or tingling.
• Vomiting, diarrhoea, fever or poor fluid intake can cause dehydration. Contact a healthcare professional promptly for advice about continuing treatment during such an illness.
• Tell the treating team that you take metformin before surgery or a scan using iodinated contrast. Treatment may need to be paused temporarily under medical direction.

Storage Instructions

• Keep tablets in their original packaging and follow the storage directions on the supplied pack.
• Keep the medicine out of children’s reach and do not use it after the expiry date.
• Ask a pharmacist how to dispose of tablets that are expired or no longer needed.

How to Take

• Take Vysov-M exactly as directed by the prescriber. The 50/500 mg strength does not determine an individual dosing schedule.
• Taking a metformin-containing tablet with food can reduce stomach upset. Follow the directions provided with your medicine.
• Do not add separate vildagliptin or metformin tablets, or change your treatment, without advice from the treating clinician.
• Ask a pharmacist or prescriber what to do if a dose is missed. Seek urgent advice if an overdose is suspected.

Drug Interactions

• Insulin and sulfonylureas can increase the chance of low blood glucose when taken with Vysov-M.
• Medicines that affect kidney function, including some diuretics, blood pressure medicines and anti-inflammatory medicines, may increase risks associated with metformin.
• Excessive alcohol intake increases the risk of lactic acidosis with metformin.
• Iodinated contrast used in some scans can affect kidney function and may require a temporary change to metformin treatment.
• Tell the prescriber or pharmacist about all other medicines and supplements you take so possible interactions can be checked.

Why Choose This Product?

• Vysov-M provides vildagliptin 50 mg and metformin hydrochloride 500 mg in one tablet.
• This fixed strength may be suitable when both ingredients form part of a prescribed type 2 diabetes treatment plan.
• The prescriber should confirm that the strength matches the required treatment and that it is appropriate for kidney and liver function.

Frequently Asked Questions (FAQs)

What is in each Vysov-M 50/500 mg tablet?

Each tablet contains vildagliptin 50 mg and metformin hydrochloride 500 mg.

What is Vysov-M used for?

It helps control blood glucose in adults with type 2 diabetes when this combination is appropriate.

Can Vysov-M treat type 1 diabetes?

No. It is not a treatment for type 1 diabetes or diabetic ketoacidosis.

How do the two ingredients work?

Vildagliptin increases incretin activity. Metformin mainly reduces glucose production by the liver and improves the response to insulin.

Can Vysov-M cause low blood glucose?

The risk is higher when it is taken with insulin or a sulfonylurea. Ask the treating team how to recognise and manage low blood glucose.

Why is kidney function checked?

Metformin is cleared through the kidneys. Poor kidney function increases the risk of metformin-related harm.

Can it be taken during pregnancy or breastfeeding?

Discuss pregnancy or breastfeeding with a healthcare professional so diabetes treatment can be reviewed.

What if stomach side effects occur?

Nausea, diarrhoea and abdominal discomfort can occur. Seek advice if symptoms persist or are severe.

Does Vysov-M replace diet and physical activity?

No. Food choices and physical activity remain part of type 2 diabetes care.

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